O33840

PR
Gene name
pulA (TM_1845)
Protein name
Pullulanase
Names
Alpha-dextrin endo-1,6-alpha-glucosidase, Pullulan 6-glucanohydrolase
Species
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
KEGG Pathway
tma:TM1845
EC number
3.2.1.41: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

633-709 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for O33840

Entry ID Method Resolution Chain Position Source
2J71 X-ray 169 A A 18-120 PDB
2J72 X-ray 149 A A/B 18-120 PDB
2J73 X-ray 140 A A/B 18-120 PDB
AF-O33840-F1 Predicted AlphaFoldDB

No variants for O33840

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O33840

No associated diseases with O33840

4 regional properties for O33840

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 13, N-terminal 224 - 304 IPR004193
domain Pullulanase, carbohydrate-binding module 41 21 - 119 IPR005323
domain Glycosyl hydrolase, family 13, catalytic domain 371 - 745 IPR006047
domain Pullulanase, type I 216 - 821 IPR011840

Functions

Description
EC Number 3.2.1.41 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
pullulanase activity Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTKLWLLLV LLLSALIFSE TTIVVHYHRY DGKYDGWNLW IWPVEPVSQE GKAYQFTGED
70 80 90 100 110 120
DFGKVAVVKL PMDLTKVGII VRLNEWQAKD VAKDRFIEIK DGKAEVWILQ GVEEIFYEKP
130 140 150 160 170 180
DTSPRIFFAQ ARSNKVIEAF LTNPVDTKKK ELFKVTVDGK EIPVSRVEKA DPTDIDVTNY
190 200 210 220 230 240
VRIVLSESLK EEDLRKDVEL IIEGYKPARV IMMEILDDYY YDGELGAVYS PEKTIFRVWS
250 260 270 280 290 300
PVSKWVKVLL FKNGEDTEPY QVVNMEYKGN GVWEAVVEGD LDGVFYLYQL ENYGKIRTTV
310 320 330 340 350 360
DPYSKAVYAN SKKSAVVNLA RTNPEGWEND RGPKIEGYED AIIYEIHIAD ITGLENSGVK
370 380 390 400 410 420
NKGLYLGLTE ENTKGPGGVT TGLSHLVELG VTHVHILPFF DFYTGDELDK DFEKYYNWGY
430 440 450 460 470 480
DPYLFMVPEG RYSTDPKNPH TRIREVKEMV KALHKHGIGV IMDMVFPHTY GIGELSAFDQ
490 500 510 520 530 540
TVPYYFYRID KTGAYLNESG CGNVIASERP MMRKFIVDTV TYWVKEYHID GFRFDQMGLI
550 560 570 580 590 600
DKKTMLEVER ALHKIDPTII LYGEPWGGWG APIRFGKSDV AGTHVAAFND EFRDAIRGSV
610 620 630 640 650 660
FNPSVKGFVM GGYGKETKIK RGVVGSINYD GKLIKSFALD PEETINYAAC HDNHTLWDKN
670 680 690 700 710 720
YLAAKADKKK EWTEEELKNA QKLAGAILLT SQGVPFLHGG QDFCRTKNFN DNSYNAPISI
730 740 750 760 770 780
NGFDYERKLQ FIDVFNYHKG LIKLRKEHPA FRLKNAEEIK KHLEFLPGGR RIVAFMLKDH
790 800 810 820 830 840
AGGDPWKDIV VIYNGNLEKT TYKLPEGKWN VVVNSQKAGT EVIETVEGTI ELDPLSAYVL
YRE