O32462

PR
Gene name
jgt (OCC_10078)
Protein name
4-alpha-glucanotransferase
Names
Amylomaltase, Disproportionating enzyme, D-enzyme
Species
Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)
KEGG Pathway
tlt:OCC_10078
EC number
2.4.1.25: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

414-493 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for O32462

Entry ID Method Resolution Chain Position Source
1K1W X-ray 280 A A 1-659 PDB
1K1X X-ray 240 A A/B 1-659 PDB
1K1Y X-ray 240 A A/B 1-659 PDB
AF-O32462-F1 Predicted AlphaFoldDB

No variants for O32462

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O32462

No associated diseases with O32462

3 regional properties for O32462

Type Name Position InterPro Accession
domain Glycoside hydrolase family 57, N-terminal domain 23 - 268 IPR004300
domain Alpha-amylase/4-alpha-glucanotransferase, central domain 311 - 383 IPR015178
domain Alpha-amylase/4-alpha-glucanotransferase, C-terminal 392 - 655 IPR015179

Functions

Description
EC Number 2.4.1.25 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
4-alpha-glucanotransferase activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
beta-maltose 4-alpha-glucanotransferase activity Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose.
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MERINFIFGI HNHQPLGNFG WVFEEAYNRS YRPFMEILEE FPEMKVNVHF SGPLLEWIEE
70 80 90 100 110 120
NKPDYLDLLR SLIKRGQLEI VVAGFYEPVL AAIPKEDRLV QIEMLKDYAR KLGYDAKGVW
130 140 150 160 170 180
LTERVWQPEL VKSLREAGIE YVVVDDYHFM SAGLSKEELF WPYYTEDGGE VITVFPIDEK
190 200 210 220 230 240
LRYLIPFRPV KKTIEYLESL TSDDPSKVAV FHDDGEKFGV WPGTYEWVYE KGWLREFFDA
250 260 270 280 290 300
ITSNEKINLM TYSEYLSKFT PRGLVYLPIA SYFEMSEWSL PAKQAKLFVE FVEQLKEEGK
310 320 330 340 350 360
FEKYRVFVRG GIWKNFFFKY PESNFMHKRM LMVSKAVRDN PEARKYILKA QCNDAYWHGV
370 380 390 400 410 420
FGGIYLPHLR RTVWENIIKA QRYLKPENKI LDVDFDGRAE IMVENDGFIA TIKPHYGGSI
430 440 450 460 470 480
FELSSKRKAV NYNDVLPRRW EHYHEVPEAT KPEKESEEGI ASIHELGKQI PEEIRRELAY
490 500 510 520 530 540
DWQLRAILQD HFIKPEETLD NYRLVKYHEL GDFVNQPYEY EMIENGVKLW REGGVYAEEK
550 560 570 580 590 600
IPARVEKKIE LTEDGFIAKY RVLLEKPYKA LFGVEINLAV HSVMEKPEEF EAKEFEVNDP
610 620 630 640 650
YGIGKVRIEL DKAAKVWKFP IKTLSQSEAG WDFIQQGVSY TMLFPIEKEL EFTVRFREL