O32450

PR
Gene name
TK1809
Protein name
4-alpha-glucanotransferase
Names
Amylomaltase, Disproportionating enzyme, D-enzyme
Species
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
KEGG Pathway
tko:TK1809
EC number
2.4.1.25: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

300-373 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O32450

Entry ID Method Resolution Chain Position Source
AF-O32450-F1 Predicted AlphaFoldDB

No variants for O32450

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O32450

No associated diseases with O32450

4 regional properties for O32450

Type Name Position InterPro Accession
domain Transketolase, N-terminal 88 - 239 IPR005474
domain Transketolase-like, pyrimidine-binding domain 288 - 453 IPR005475
binding_site Transketolase binding site 396 - 412 IPR020826
domain Transketolase, C-terminal domain 465 - 586 IPR033248

Functions

Description
EC Number 2.4.1.25 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
4-alpha-glucanotransferase activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
beta-maltose 4-alpha-glucanotransferase activity Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose.
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEMVNFIFGI HNHQPLGNFG WVMESAYERS YRPFMETLEE YPNMKVAVHY SGPLLEWIRD
70 80 90 100 110 120
NKPEHLDLLR SLVKRGQLEI VVAGFYEPVL ASIPKEDRIV QIEKLKEFAR NLGYEARGVW
130 140 150 160 170 180
LTERVWQPEL VKSLRAAGID YVIVDDYHFM SAGLSKDELF WPYYTEDGGE VITVFPIDEK
190 200 210 220 230 240
LRYLIPFRPV DKTLEYLHSL DDGDESKVAV FHDDGEKFGV WPGTYEWVYE KGWLREFFDR
250 260 270 280 290 300
VSSDERINLM LYSEYLQRFR PRGLVYLPIA SYFEMSEWSL PARQAKLFVE FVEELKKENK
310 320 330 340 350 360
FDRYRVFVRG GIWKNFFFKY PESNYMHKRM LMVSKAVRNN PEAREFILRA QCNDAYWHGV
370 380 390 400 410 420
FGGVYLPHLR RAVWENIIKA QSHVKTGNFV RDIDFDGRDE VFIENENFYA VFKPAYGGAL
430 440 450 460 470 480
FELSSKRKAV NYNDVLARRW EHYHEVPEAA TPEEGGEGVA SIHELGKQIP DEIRRELAYD
490 500 510 520 530 540
SHLRAILQDH FLEPETTLDE YRLSRYIELG DFLTGAYNFS LIENGITLER DGSVAKRPAR
550 560 570 580 590 600
VEKSVRLTED GFIVDYTVRS DARALFGVEL NLAVHSVMEE PAEFEAEKFE VNDPYGIGKV
610 620 630 640 650
EIELDRRAKV WKYPIKTLSQ SESGWDFIQQ GVSYTVLFPV EGELRFRLRF REL