O32037
Gene name |
tcdA (yrvM, BSU27540) |
Protein name |
tRNA threonylcarbamoyladenosine dehydratase |
Names |
t(6)A37 dehydratase |
Species |
Bacillus subtilis (strain 168) |
KEGG Pathway |
bsu:BSU27540 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O32037
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O32037-F1 | Predicted | AlphaFoldDB |
No variants for O32037
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O32037 | |||||
No associated diseases with O32037
1 regional properties for O32037
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | THIF-type NAD/FAD binding fold | 7 - 232 | IPR000594 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tRNA threonylcarbamoyladenosine dehydratase | Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A. |
| ubiquitin-like modifier activating enzyme activity | Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cyclic threonylcarbamoyladenosine biosynthetic process | The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLHQFSRNEL | AIGKEGLETL | KNSTVAVLGV | GGVGSFAAEA | LARSGVGRIL | LVDKDDVDIT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVNRQLHALL | STVGQPKVDL | MKARIADINP | ECEVIALKMF | YTEETYEQFF | DYGLDYVIDA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SDTICYKIHL | MKECLKRDIP | LISSMGAANK | TDPTRFQIAD | ISKTHTDPIA | KVVRTKLRKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GIKKGVQVIF | SDESPIVIRE | DVRKEVGNDE | AKIRKAKMPP | SSNAFVPSVA | GLIMGGHVVM |
| 250 | |||||
| DLLKDIEIKR | VKDK |