O31774

PR
Gene name
rny (ymdA, BSU16960)
Protein name
Ribonuclease Y
Names
RNase Y
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU16960
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-216 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for O31774

Entry ID Method Resolution Chain Position Source
6F7T X-ray 260 A C/D 79-90 PDB
AF-O31774-F1 Predicted AlphaFoldDB

No variants for O31774

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O31774

No associated diseases with O31774

6 regional properties for O31774

Type Name Position InterPro Accession
domain HD/PDEase domain 331 - 437 IPR003607
domain K Homology domain 207 - 274 IPR004087
domain K Homology domain, type 1 213 - 266 IPR004088
domain HD domain 335 - 428 IPR006674
domain HDIG domain 331 - 408 IPR006675
domain Ribonuclease Y, N-terminal 5 - 204 IPR022711

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass membrane protein
  • Dispersed along membrane with a few foci at septation sites and cell poles; in the absence of dynA fewer foci are seen, in the absence of minJ no foci are seen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
identical protein binding Binding to an identical protein or proteins.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPIMMVLIS ILLILLGLVV GYFVRKTIAE AKIAGARGAA EQILEDAKRD AEALKKEALL
70 80 90 100 110 120
EAKDEIHKLR IDAEQEVRER RNELQKQENR LLQKEENLDR KHEGIDKREA MLEKKDHSLN
130 140 150 160 170 180
ERQQHIEEME SKVDEMIRMQ QSELERISSL TRDEAKQIIL ERVENELSHD IAIMTKETEN
190 200 210 220 230 240
RAKEEADKKA KNILSLALQR CAADHVAETT VSVVNLPNDE MKGRIIGREG RNIRTLETLT
250 260 270 280 290 300
GIDLIIDDTP EAVILSGFDP IRRETARIAL DKLVQDGRIH PARIEEMVEK SRREVDDYIR
310 320 330 340 350 360
EMGEQTTFEV GVHGLHPDLI KILGRLKFRT SYGQNVLKHS MEVAFLAGLM ASELGEDAKL
370 380 390 400 410 420
AKRAGLLHDI GKAIDHEVEG SHVEIGVELA TKYKEHPVVI NSIASHHGDE EPTSIIAVLV
430 440 450 460 470 480
AAADALSAAR PGARSETLEN YIRRLEKLEE ISESYEGVEK SFAIQAGREV RIMVKPDSIN
490 500 510
DLEAHRLARD IRKRIEDELD YPGHIKVTVI RETRAVEYAK