O31751
Gene name |
uppS |
Protein name |
Isoprenyl transferase |
Names |
|
Species |
Bacillus subtilis (strain 168) |
KEGG Pathway |
bsu:BSU16530 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for O31751
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7JLI | X-ray | 180 A | A | 1-260 | PDB |
| 7JLJ | X-ray | 310 A | A | 1-260 | PDB |
| 7JLM | X-ray | 230 A | A/B | 1-260 | PDB |
| 7JLR | X-ray | 220 A | A | 1-260 | PDB |
| AF-O31751-F1 | Predicted | AlphaFoldDB |
No variants for O31751
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O31751 | |||||
No associated diseases with O31751
1 regional properties for O31751
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Di-trans-poly-cis-decaprenylcistransferase-like, conserved site | 176 - 193 | IPR018520 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| di-trans,poly-cis-decaprenylcistransferase activity | Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| manganese ion binding | Binding to a manganese ion (Mn). |
| polyprenyltransferase activity | Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| polyprenol biosynthetic process | The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLNILKNWKN | QQTAASNLER | YTKEDILKGE | IPEHIAIIMD | GNGRWAKKRS | LPRIAGHHEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MKVVKRTTKL | ANELGVKVLT | LYAFSTENWK | RPKMEVDFLM | KLPEEFLNTY | LPELVEENVQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VRIIGDETAL | PAHTLRAIEK | AVQDTAQNDG | MILNFALNYG | GRTEIVSAAK | SLAEKVKEGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LNIEDIDESL | FSTYLMTESL | QDPELLIRTS | GEIRLSNFML | WQVAYSEFVF | TDVLWPDFKE |
| 250 | |||||
| DHFLQALGEF | QQRGRRFGGI |