O31749

PR
Gene name
pyrH (smbA, BSU16510)
Protein name
Uridylate kinase
Names
UK, Uridine monophosphate kinase, UMP kinase, UMPK
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU16510
EC number
2.7.4.22: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

59-135 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O31749

Entry ID Method Resolution Chain Position Source
AF-O31749-F1 Predicted AlphaFoldDB

No variants for O31749

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O31749

No associated diseases with O31749

1 regional properties for O31749

Type Name Position InterPro Accession
domain Aspartate/glutamate/uridylate kinase 7 - 217 IPR001048

Functions

Description
EC Number 2.7.4.22 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
  • Is predominantly localized near the bacterial membranes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
UMP kinase activity Catalysis of the reaction: ATP + UMP = ADP + UDP.

3 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
UDP biosynthetic process The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKPKYKRIV LKLSGEALAG EQGNGINPTV IQSIAKQVKE IAELEVEVAV VVGGGNLWRG
70 80 90 100 110 120
KTGSDLGMDR ATADYMGMLA TVMNSLALQD SLETLGIQSR VQTSIEMRQV AEPYIRRKAI
130 140 150 160 170 180
RHLEKKRVVI FAAGTGNPYF STDTTAALRA AEIEADVILM AKNNVDGVYN ADPRKDESAV
190 200 210 220 230
KYESLSYLDV LKDGLEVMDS TASSLCMDND IPLIVFSIME EGNIKRAVIG ESIGTIVRGK