O31073
Gene name |
sacIM |
Protein name |
Type II methyltransferase M.SacI |
Names |
M.SacI, Cytosine-specific methyltransferase SacI, Modification methylase SacI |
Species |
Streptomyces achromogenes |
KEGG Pathway |
|
EC number |
2.1.1.37: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O31073
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O31073-F1 | Predicted | AlphaFoldDB |
No variants for O31073
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O31073 | |||||
No associated diseases with O31073
No regional properties for O31073
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O31073 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.37 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA (cytosine-5-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA restriction-modification system | A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNHELPVISL | FSGAGGLDCA | IESCAEPPLV | QDGSGSPLRV | AVATDYEQTA | LDTLSANFPH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TKTLCGDIQT | IPTAELLEAG | GLKPGDPTLV | IGGPPCTPFS | KSGFWIEEKR | NSADPNASLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEYVRVVRES | KPEAFILENV | QGLTYKTHQA | QFDRLIAGLK | DAGYNPTFRV | LLAAEYGVPQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRRRVFVVGR | RDGKAFHFPE | TTHSGESERD | RVIDHTKIPF | TSLREALAGL | PDVPEAGEVV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EGTYAELAAE | VPPGQNYLWH | TDRYGGRNEF | KWRSRYWTFL | LKADPDRPST | TLQAQPGPWV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GPFHWENVKN | ANGEERARRF | RVAEMKRIMT | FPDEFVFTGV | KREVQRQIGN | PVPVELGKVV |
| 370 | 380 | ||||
| VRALMEQLGY | LDSRGTTIPS | QAGHEQLELI |