O30085

PR
Gene name
copB (AF_0152)
Protein name
Copper-exporting P-type ATPase B
Names
Species
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
KEGG Pathway
afu:AF_0152
EC number
7.2.2.9: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for O30085

Entry ID Method Resolution Chain Position Source
3SKX X-ray 159 A A 372-636 PDB
3SKY X-ray 210 A A 372-636 PDB
AF-O30085-F1 Predicted AlphaFoldDB

No variants for O30085

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O30085

No associated diseases with O30085

2 regional properties for O30085

Type Name Position InterPro Accession
ptm P-type ATPase, phosphorylation site 389 - 395 IPR018303
domain P-type ATPase, haloacid dehalogenase domain 369 - 633 IPR044492

Functions

Description
EC Number 7.2.2.9 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type divalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHEHDSHGEA AHSNSEDMQM IHQHHEHHGH EEEHSAHHEK MKHSADHGDH HRMMMEDFKK
70 80 90 100 110 120
RFYVSTLLTI PILILSPAIQ TFLGFRVEFA GSLYILFLLS SAVYFYGGYP FLKGIFDELR
130 140 150 160 170 180
RRQPGMMTLI AVAISVAYFY SSAVVFGLKG KFFFWELATL IDIMLLGHYI EMRSVLGASR
190 200 210 220 230 240
ALEELVKIMP SEAHLLKDGE IVEVKVENLK PGDKVLVKPG EKIPVDGIVV EGESFVNEAM
250 260 270 280 290 300
LTGESKPVAK KPGDTVIGGA INGEGSLVVE VEKTGKDTYL NQVIELVRQA QESKSRTQDL
310 320 330 340 350 360
ANRAALLLTV IALTVGSVTL AIWLAYIADF AFAIERAVTV MVITCPHALG LAIPLVVAVS
370 380 390 400 410 420
TSLAAKSGLL IRDRQAFERA KDLQAVIFDK TGTLTEGRFG VTDIVGFNHS EDELLQIAAS
430 440 450 460 470 480
LEARSEHPIA AAIVEEAEKR GFGLTEVEEF RAIPGKGVEG IVNGRRYMVV SPGYIRELGI
490 500 510 520 530 540
KTDESVEKLK QQGKTVVFIL KNGEVSGVIA LADRIRPESR EAISKLKAIG IKCMMLTGDN
550 560 570 580 590 600
RFVAKWVAEE LGLDDYFAEV LPHEKAEKVK EVQQKYVTAM VGDGVNDAPA LAQADVGIAI
610 620 630 640 650 660
GAGTDVAVET ADIVLVRNDP RDVAAIVELS RKTYSKMKQN LLWATGYNAF AIPLAAGVLY
670 680
SAGILLSPAV GAILMSLSTV IVAINARLLR