O29904

PR
Gene name
AF_0343
Protein name
NAD(P)H dehydrogenase (quinone)
Names
Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO
Species
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
KEGG Pathway
afu:AF_0343
EC number
1.6.5.2: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-96 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O29904

Entry ID Method Resolution Chain Position Source
AF-O29904-F1 Predicted AlphaFoldDB

No variants for O29904

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O29904

No associated diseases with O29904

3 regional properties for O29904

Type Name Position InterPro Accession
conserved_site Flavodoxin, conserved site 6 - 22 IPR001226
domain NADPH-dependent FMN reductase-like 3 - 145 IPR005025
domain Flavodoxin/nitric oxide synthase 4 - 184 IPR008254

Functions

Description
EC Number 1.6.5.2 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
electron transfer activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
NADH dehydrogenase (quinone) activity Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
NADPH dehydrogenase (quinone) activity Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARILVIFHS ITGNTMKLAK AVADGAREGG AEVAVKRVPE TIPAEILEKN PGYVKVREEL
70 80 90 100 110 120
ESFEVARPEE LQDYDAIIFG SPTRFGVMSS QMKQFIDMTG RLWMERRLEG KVGAVFTSNE
130 140 150 160 170 180
MPHGGKEATL LSMLLPLFAH GMIIVGLPPA KELYRAGSYY GAASTGVPKE DDLQVAKMLG
190
KRVAEVAEKL C