O29665

PR
Gene name
hisG (AF_0590)
Protein name
ATP phosphoribosyltransferase
Names
ATP-PRT, ATP-PRTase
Species
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
KEGG Pathway
afu:AF_0590
EC number
2.4.2.17: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

126-200 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O29665

Entry ID Method Resolution Chain Position Source
AF-O29665-F1 Predicted AlphaFoldDB

No variants for O29665

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O29665

No associated diseases with O29665

2 regional properties for O29665

Type Name Position InterPro Accession
domain Histidine biosynthesis HisG, C-terminal 153 - 252 IPR013115
domain ATP phosphoribosyltransferase, catalytic domain 2 - 174 IPR013820

Functions

Description
EC Number 2.4.2.17 Pentosyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP phosphoribosyltransferase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRPQIMPFYI EMGKGDGGIT GEDILQNWML KSNLKNVEIL EELPLRPTKL VVAISEEIYP
70 80 90 100 110 120
DVYTIEDFKE KVGDREVFIA SEFPEIARKY AEKHGLNAIV FDPIGKTEAA LLPPMPEADL
130 140 150 160 170 180
IIEITEFGTT LKENMCRIID LVMDKVHSVF IVNKESLKDE EKKQVMENLV TDLKEVIESR
190 200 210 220 230 240
NLVSFYFNVP NEDDLRRIID YLTENGFDPT ISPLAKGGAA VHIIVDRSRV KFLKPIIRGM
250 260 270 280
GAKRIATSPV ITSGTNRAAQ QKPFYLLSGI QREFPSASPF F