O29231
Gene name |
mre11 |
Protein name |
DNA double-strand break repair protein Mre11 |
Names |
|
Species |
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) |
KEGG Pathway |
afu:AF_1031 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O29231
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O29231-F1 | Predicted | AlphaFoldDB |
No variants for O29231
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O29231 | |||||
No associated diseases with O29231
No regional properties for O29231
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O29231 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3'-5' exonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. |
| DNA end binding | Binding to DNA ends exposed by the creation of double-strand breaks (DSBs). |
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| manganese ion binding | Binding to a manganese ion (Mn). |
| Y-form DNA binding | Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| double-strand break repair | The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFAHIADVH | LGYEQYNQPW | RAEDFAKAFK | VIAEKAVESN | ADFVVIAGDL | FHRSLPSPRT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IKEAVETLWM | FRKENIPVFA | VEGNHDKTSR | DISAYHLLES | LGLLNVLGLR | RNPVRGENVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SLRIQNVYLV | KGVVDDVEIL | GDRHRSKWQL | EKVLPLLKPQ | SDKSVLVLHQ | AVKEVVDIDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DMAYELTIND | LPEASYYAFG | HIHLPKIYEF | DGKAIAYPGS | VERYDLREAS | KIVRYRDELV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LKDGIRKGFI | LVKNFRPEFV | EIETRELYDV | EIEDESVEGL | EKKFLEVLGR | ADKEGIMVAK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LKSSDAVDVR | RLSEVAAKRV | RYAEIRFERI | LEEIEEVEIK | QESEFFTEFE | LKLLELLRGE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MDEDEVYSLV | VEHYLSGGAL | KQEEGAEERV | VEEETEKKVE | EQFKGDEEAD | EAERRAEETE |
| 430 | 440 | ||||
| KAKSTKKARK | PKTLLDFLGV | EEE |