O27937

PR
Gene name
rtcA (MTH_1915)
Protein name
RNA 3'-terminal phosphate cyclase
Names
RNA cyclase, RNA-3'-phosphate cyclase
Species
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
KEGG Pathway
mth:MTH_1915
EC number
6.5.1.4: Forming phosphoric ester bonds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O27937

Entry ID Method Resolution Chain Position Source
AF-O27937-F1 Predicted AlphaFoldDB

No variants for O27937

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O27937

No associated diseases with O27937

3 regional properties for O27937

Type Name Position InterPro Accession
domain RNA 3'-terminal phosphate cyclase, insert domain 180 - 273 IPR013791
conserved_site RNA 3'-terminal phosphate cyclase-like, conserved site 154 - 164 IPR020719
domain RNA 3'-terminal phosphate cyclase domain 9 - 324 IPR023797

Functions

Description
EC Number 6.5.1.4 Forming phosphoric ester bonds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
RNA-3'-phosphate cyclase activity Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.

1 GO annotations of biological process

Name Definition
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIVIDGSEGE GGGAVVRVST ALAAVTSRSV RVYNIRARRS RSGLSHQHLT AVRAVARISN
70 80 90 100 110 120
GTLRGDELGS MELEFSPGRV TGGTFNFDVK TAGSTGLVLQ AIMVAAAASE GEIDVTVSGG
130 140 150 160 170 180
TDVLWAPTCD YLREVTIPVL EMMGYSARIE IIRRGYYPEG GGRVHAIIEP SELRPITLEE
190 200 210 220 230 240
SEIHAVRGIS HSRNLPVHVA ERQAESAMKI LRGAGLDVDI MVEDASGPVG RGSGITLWAE
250 260 270 280 290 300
GNTRLGAVSL GKPGKRAEKV GSEAARELLG FIESGSPLDR YMGDQIIPYM ALTGDSRVRT
310 320 330
CELTLHAETN IILSEKITGR RFRVEGERGG PATIEVL