O27906

PR
Gene name
hdrC (MTH_1878)
Protein name
H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit C
Names
CoB--CoM heterodisulfide reductase iron-sulfur subunit C
Species
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
KEGG Pathway
mth:MTH_1878
EC number
1.8.98.5: With other, known, acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O27906

Entry ID Method Resolution Chain Position Source
AF-O27906-F1 Predicted AlphaFoldDB

No variants for O27906

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O27906

No associated diseases with O27906

2 regional properties for O27906

Type Name Position InterPro Accession
domain 4Fe-4S ferredoxin-type, iron-sulphur binding domain 25 - 93 IPR017896
conserved_site 4Fe-4S ferredoxin, iron-sulphur binding, conserved site 79 - 90 IPR017900

Functions

Description
EC Number 1.8.98.5 With other, known, acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
CoB--CoM heterodisulfide reductase activity Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
methanogenesis The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLLQREENI IRKGNIDKEF SEKIKAAGGD SLEYCFQCGT CTGSCPSGRR TPYRVRQIIR
70 80 90 100 110 120
KANVGLKDEI ISDPALWMCT TCYSCQERCP RKVKIVDVVK LARNEAAKAG FMAPAHKAVG
130 140 150 160 170 180
SFVIKTGHGV PINDATMELR KAVGLGELPP TTHQFPEALE EVQKIIKATG FDQLIGYNWE
TGELE