O27753
Gene name |
MTH_1718 |
Protein name |
Digeranylgeranylglycerophospholipid reductase 2 |
Names |
DGGGPL reductase 2, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase 2, Geranylgeranyl reductase 2, GGR 2 |
Species |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) |
KEGG Pathway |
mth:MTH_1718 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O27753
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O27753-F1 | Predicted | AlphaFoldDB |
No variants for O27753
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O27753 | |||||
No associated diseases with O27753
No regional properties for O27753
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O27753 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
| geranylgeranyl reductase activity | Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group. |
| oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| glycerophospholipid metabolic process | The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. |
| membrane lipid biosynthetic process | The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. |
| phospholipid biosynthetic process | The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKYDVVVIGG | RVAGSTAAYH | AARLGLSVLL | LERNPEIGTP | VQCAGGVSDS | FFKSTGLKPL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PEFTCTRIRA | AAVNGPLGAR | IVTENPVVRG | YILERKSLDK | YLALRAAEAG | ADVLTMSIAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DLIFREGSVS | GVVFRGPDGV | QEVECGMVIA | ADGVQSSIAR | KAGLETGFRP | ADLCSCVQYE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VAGVDVDPET | MEFYFGSRFA | PSGYLWVFPK | GEGRANVGLG | IRRKSCSERG | PLSYLNRFME |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ERGFKRIEFN | AGAVPVCGPI | ERTFTDGLLV | VGDAAGQVDP | LTGGGIHLAA | ECAKIAGEVA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AEAIESGRVD | GRFLSRYEMR | WRKKIGKNLE | RSLKFRKILD | GLGDEELDAL | LRSLEGKDLS |
| 370 | 380 | ||||
| SISKISLLRI | LKDYPSMLRI | LRDIL |