O27696
Gene name |
trpB1 (trpB, MTH_1659) |
Protein name |
Tryptophan synthase beta chain 1 |
Names |
|
Species |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) |
KEGG Pathway |
mth:MTH_1659 |
EC number |
4.2.1.20: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O27696
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O27696-F1 | Predicted | AlphaFoldDB |
No variants for O27696
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O27696 | |||||
No associated diseases with O27696
4 regional properties for O27696
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA recognition motif domain | 6 - 89 | IPR000504-1 |
| domain | RNA recognition motif domain | 99 - 178 | IPR000504-2 |
| domain | SECp43, RNA recognition motif 2 | 98 - 179 | IPR034510 |
| domain | tRNA selenocysteine 1-associated protein 1, C-terminal | 189 - 310 | IPR041085 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.20 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tryptophan synthase activity | Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIMDGKFGKY | GGIFVPELLI | PALEELERAF | LHYRDDRKFM | AELEYHLREY | AGKPTGLYYA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RNLSEKLGCR | VYLKREDMLH | TGAHKINNTI | GQALLARYMG | KTRIIAETGA | GQHGIATAAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GALFGMDVDI | YMGTEDVERQ | KLNVFRMEVS | GAEVIPVDSG | SRTLKDAINE | AMRDWISNVD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DTHYLIGSTM | GPHPYPTMVK | HFQSVIGREA | REQILEVEGE | LPDTVIACVG | GGSNAIGIFS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AFMDDDVELI | GAEGGGEGIE | SGNHGATLSA | GSEGILHGSL | SYVLQDGDGQ | ISEAHSVSAG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LDYPGVGPEH | AHLMDTGRAR | YEPVTDTEAL | RGFRLLSRYE | GIMPALESAH | AIACLERYAE |
| 370 | 380 | 390 | |||
| KPENRGKTVI | VNLSGRGDKD | MFMVAGLLGV | GV |