O27392
Gene name |
argD |
Protein name |
Acetylornithine aminotransferase |
Names |
ACOAT |
Species |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) |
KEGG Pathway |
mth:MTH_1337 |
EC number |
2.6.1.11: Transaminases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O27392
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O27392-F1 | Predicted | AlphaFoldDB |
No variants for O27392
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O27392 | |||||
No associated diseases with O27392
No regional properties for O27392
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O27392 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.6.1.11 | Transaminases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity | Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine biosynthetic process | The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSEEIIELE | RKFIMQTYTR | QPIVLSHGKG | ATVWDIEGNS | YIDCFAGVAV | NSIGHAHPKV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALAICHQAQR | LIHSSNIYYT | REQVELAKLL | TAISPHDRVF | FANSGAEANE | GAIKLARKFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKSEIIAAEN | SFHGRTLATV | TATGQKKYSE | PFRPLPEGFK | HVPYGDIGAM | ADAVGDETAA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IILEPVQGEG | GVIIPPEGYL | KDVQELARQN | DVLLILDEVQ | TGFGRTGAMF | ASQLFGVEPD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ITTVAKAMGG | GYPIGAVLAN | ERVAMAFEPG | DHGSTFGGNP | WGCAAAIATI | EVLMDEKLPE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RAAKMGSYFL | GRLRQVLHGC | DAVRDIRGVG | LMIGIEIDGE | CAGVVDAARE | MGVLINCTAG |
| 370 | 380 | ||||
| KVIRIVPPLV | IKKEEIDAAV | DVLGHVISDL |