O27363

PR
Gene name
eif2a (MTH_1308)
Protein name
Translation initiation factor 2 subunit alpha
Names
aIF2-alpha, eIF-2-alpha
Species
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
KEGG Pathway
mth:MTH_1308
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O27363

Entry ID Method Resolution Chain Position Source
AF-O27363-F1 Predicted AlphaFoldDB

No variants for O27363

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O27363

No associated diseases with O27363

3 regional properties for O27363

Type Name Position InterPro Accession
domain S1 domain 12 - 86 IPR003029
domain RNA-binding domain, S1 13 - 86 IPR022967
domain IF2a, S1-like domain 12 - 87 IPR044126

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFFMVRRKNE WPEEGELVVG TVHKVLNYGA FATLEEYPGK EAFIHISEVS SGWVKNIRDF
70 80 90 100 110 120
VRENQKIVAR VLRVNPRKGH VDVSMKRIRE DQRTKKIQAW KIEQKAEKFL ELAARDLGKD
130 140 150 160 170 180
LDTAYEEVGY ELMDIFGDLY GAFETAAEEG EKSLIEEGVP EDWAAVITEV AKRNITPPEV
190 200 210 220 230 240
QITGYVDIKS YAPNGVEIIR KALKSAQDEG ITVQAVGAPR YRLIVKSTDY LKAEKQLKEA
250 260
AQKCIEIVEK EGGEGEFLRE LT