O26278
Gene name |
tgtA |
Protein name |
tRNA-guanine(15) transglycosylase |
Names |
7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase |
Species |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum) |
KEGG Pathway |
mth:MTH_176 |
EC number |
2.4.2.48: Pentosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O26278
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O26278-F1 | Predicted | AlphaFoldDB |
No variants for O26278
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O26278 | |||||
No associated diseases with O26278
4 regional properties for O26278
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.2.48 | Pentosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| pentosyltransferase activity | Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTLWEDFMFE | IKSKDGLGRT | GILKTEHGTV | RTPALMPVIH | PGKQTIDVKG | PGAEIVITNA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YIIYRNPELR | ERALSDGVHR | LIDFDGPIMT | DSGSFQLSEY | GDIEVENPEI | IRFQDEIGTD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGTSLDIPTP | PGVSHRRAIE | EVEVTLERAR | ESIEYRERMM | LNAVVQGSTH | PDLRRYCASR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LAELPVELHP | IGAVVPLMES | YRYRELVDAV | LSSVSELPPS | RPRHLMGAGH | PMLFALAVSM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GCDLFDSAAY | ILYAEDDRLL | STEGTYKLEN | LQEMPCSCSV | CTDYTPSELM | GMDREERRNL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IAEHNLHVSF | AEIRKVRQAI | HDGNLMELVE | ERCRAHPRLL | EGYRRMSEYL | DLIEKFEPRS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KRSAFFYTGP | ESLGRVEVHR | HLKRVKEHLG | ERLALVAPSR | RPYSSSLPAR | IGGFSSLRPQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SGGPWRVVVV | DLPFGIIPLE | LDQVYPLAQS | DAPGIMDLDG | EEFLRGLVRD | LMDGDAIVDD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ALCSELGIEL | PYKYMGEVET | TVDDLDRVRM | VADYQFGMGA | GELLFTDDVR | IERSRNTGKI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RHIYAGDELI | CTMRASDGLL | VLGAEGAVRL | HKGTDYPAWR | VAVNEESEPF | ARKGKSVFAK |
| 610 | 620 | 630 | 640 | 650 | |
| FIIDCDNNIR | ANDEVLIVNA | DDELLATGKA | LLCAEEMMDL | NHGQAVKTRK | GGF |