O25042

PR
Gene name
hpyAIR
Protein name
Probable type II restriction enzyme HpyAORF263P
Names
HpyAORF263P, Endonuclease HpyAORF263P, Type-2 restriction enzyme HpyAORF263P
Species
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
KEGG Pathway
hpy:HP_0262
EC number
3.1.21.4: Endodeoxyribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O25042

Entry ID Method Resolution Chain Position Source
AF-O25042-F1 Predicted AlphaFoldDB

No variants for O25042

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O25042

No associated diseases with O25042

1 regional properties for O25042

Type Name Position InterPro Accession
domain BsaWI restriction endonuclease type 2 105 - 188 IPR041551

Functions

Description
EC Number 3.1.21.4 Endodeoxyribonucleases producing 5'-phosphomonoesters
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFGLGLADVI LERFKDFMRE QPEPYKFLQV FYAQEKERFL NHKMSDYIKQ NKSKEEASIL
70 80 90 100 110 120
ARQGFVSAVG RALEKIIELL LKDFCIKNNV KMTNDKILRA KRINGELDRV KRALWVHFGE
130 140 150 160 170 180
YSVLPDIILY QTNKDNIKIL AILSVKNSFR ERFTETPYWK LKLLQSPVTS HIKVFMITPD
190
NDDEISFKDK PKG