O24241
Gene name |
FPS1 |
Protein name |
Farnesyl pyrophosphate synthase 1 |
Names |
FPP synthase 1, FPS 1, (2E,6E)-farnesyl diphosphate synthase 1, Dimethylallyltranstransferase 1, Farnesyl diphosphate synthase 1, Geranyltranstransferase 1 |
Species |
Parthenium argentatum (Guayule rubber plant) |
KEGG Pathway |
|
EC number |
2.5.1.1: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O24241
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O24241-F1 | Predicted | AlphaFoldDB |
No variants for O24241
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O24241 | |||||
No associated diseases with O24241
No regional properties for O24241
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O24241 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.1 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| dimethylallyltranstransferase activity | Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. |
| geranyltranstransferase activity | Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate. |
| metal ion binding | Binding to a metal ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cholesterol biosynthetic process | The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
| farnesyl diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of farnesyl diphosphate. |
| geranyl diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of geranyl diphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSDLKSRFL | QVYDTLKSEL | INDPAFEFDD | DSRQWVEKML | DYNVPGGKLN | RGLSVIDSYQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLKGGELTDN | EIFLAAALGW | CIEWLQAYFL | VLDDIMDESH | TRRGQPCWFR | LPKVGMIAAN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGIILRNNVP | RILKKHFRGK | PYYVDLLDLF | NEVEFQTASG | QMIDLITTLV | GEKDLSKYSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SIHRRIVQYK | TAYYSFYLPV | ACALLMFGED | LEKHEEVKNV | LVEMGTYFQV | QDDYLDCFGA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PEVIGKIGTD | IEDFKCSWLV | VKALELSNEE | QKKILHENYG | KKDPSSVAKV | KELYHTLNLQ |
| 310 | 320 | 330 | 340 | ||
| GVFEDYENTS | YKKLITSIEG | HPSKAVQAVL | KSFLGKIYKR | QK |