Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O23317
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O23317-F1 | Predicted | AlphaFoldDB |
No variants for O23317
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O23317 | |||||
No associated diseases with O23317
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP binding | Binding to ADP, adenosine 5'-diphosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F1MHT9 | NLRC4 | NLR family CARD domain-containing protein 4 | Bos taurus (Bovine) | SS |
| Q9NPP4 | NLRC4 | NLR family CARD domain-containing protein 4 | Homo sapiens (Human) | SS |
| Q3UP24 | Nlrc4 | NLR family CARD domain-containing protein 4 | Mus musculus (Mouse) | EV |
| F1M649 | Nlrc4 | NLR family CARD domain-containing protein 4 | Rattus norvegicus (Rat) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALTKLRFVN | QFSQWLCVRK | GYIHSLPENL | AALQKAIEVL | KTKHDDVKRR | VDKEEFLGRR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HRLSQVQVEI | ERLCFCGFCS | KSFGKSYHYG | KMVSVMLKEV | ENLSSRGVFD | VVTEENLVAQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEEMPIQSTV | VGQETMLERV | WNTLMKDGFK | IMGLYGMGGV | GKTTLLTQIN | KKFSETDGGF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DIVMWVVVSK | TSEIYRIQED | IAKRLGLTGE | EWDKKNENKR | AVDIHNVLRR | HKFVLLLDDI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WEKVNLELVG | VPYPSRENGS | IVAFTTRSRD | VCGRMGVDDP | MQVSCLEPED | AWDLFQNKVG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ENTLKSHPDI | PELAKQVAEK | CRGLPLALNV | IGETMACKST | VQEWRHAIDE | EWKKTEVKMH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DVVREMALWI | SSDLGKHKDQ | CIVRAGVGLH | AVPEVKNWRA | VRRMSLMKNE | LEKILGCPTC |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PQLTTLLLQK | NHKLVNISGE | FFRFMPNLVV | LDLSWNSSLT | GLPKKISEVE | TTNTSEFGVH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EEFGEYAGVS | KLLSLKTLRL | QKSKKALDVN | SAKELQLLEH | IEVLTIDIFS | KVEEESFKIL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TFPSMCNIRR | IGIWKCGMKE | IKVEMRTSSC | FSSLSKVVIG | QCDGLKELTW | LLFAPNLTYL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DARFAEQLED | IISEEKAASV | TDENASIIIP | FQKLECLSLS | DLPKLKSIYW | SPLSFPRLSE |
| 670 | 680 | 690 | 700 | 710 | |
| LAVQEHCPKL | KKLPLNSKSG | TAGVELVVKY | GENKWLEGVE | WEDKATELRF | LATCKSLYR |