O22944

PR
Gene name
NTAQ1
Protein name
Protein N-terminal glutamine amidohydrolase
Names
Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G41760
EC number
3.5.1.122: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

119-189 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O22944

Entry ID Method Resolution Chain Position Source
AF-O22944-F1 Predicted AlphaFoldDB

19 variants for O22944

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_17422868_C_T 2 S>F No 1000Genomes
ENSVATH14606517 3 G>A No 1000Genomes
ENSVATH05699669 9 I>L No 1000Genomes
tmp_2_17423145_C_T 33 T>M No 1000Genomes
ENSVATH01978508 38 G>A No 1000Genomes
ENSVATH00269872 41 E>D No 1000Genomes
ENSVATH01978509 44 C>G No 1000Genomes
ENSVATH01978510 49 V>A No 1000Genomes
tmp_2_17423402_G_A 73 V>I No 1000Genomes
ENSVATH01978519 88 E>G No 1000Genomes
tmp_2_17423604_G_A 112 V>M No 1000Genomes
tmp_2_17423641_C_T 124 A>V No 1000Genomes
ENSVATH01978525 170 D>H No 1000Genomes
ENSVATH01978528 174 H>Y No 1000Genomes
tmp_2_17424175_G_C 196 V>L No 1000Genomes
ENSVATH00269883 197 T>I No 1000Genomes
tmp_2_17424193_C_G 202 Q>E No 1000Genomes
ENSVATH01978529 204 L>F No 1000Genomes
ENSVATH00269885 218 T>I No 1000Genomes

No associated diseases with O22944

No regional properties for O22944

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O22944

Functions

Description
EC Number 3.5.1.122 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
protein-N-terminal asparagine amidohydrolase activity Catalysis of the reaction: N-terminal L-asparaginyl-
protein-N-terminal glutamine amidohydrolase activity Catalysis of the reaction: N-terminal L-glutaminyl-

3 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
positive regulation of camalexin biosynthetic process Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.
protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGVTSEPIA MDATRFQHTP YYCEENVYLL CKTLCENGVA EATCSDLFVV FISNEKKQVP
70 80 90 100 110 120
LWHQKASTRA DGVVLWDYHV ICVQRKKESD SEPLVWDLDS TLPFPSPLAS YVTETIQPSF
130 140 150 160 170 180
QLFAEYQRFF RIVHAPLFFK HFASDRRHMK EPDGSWTAQP PPYEPIVAQD GILHNLSEYI
190 200 210 220
AMSGADTLSS LDPETVTAAI SQKLGVVVSH TQLQDLFTKL P