Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O22288

Entry ID Method Resolution Chain Position Source
AF-O22288-F1 Predicted AlphaFoldDB

49 variants for O22288

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01969420 3 F>L No 1000Genomes
tmp_2_16594882_C_T 17 A>V No 1000Genomes
ENSVATH01969421 18 C>Y No 1000Genomes
tmp_2_16594911_G_A 27 V>I No 1000Genomes
ENSVATH05686172 29 N>Y No 1000Genomes
ENSVATH01969422 31 P>L No 1000Genomes
tmp_2_16594927_C_G 32 S>C No 1000Genomes
tmp_2_16594999_A_G 56 K>R No 1000Genomes
tmp_2_16595038_C_G 69 S>C No 1000Genomes
tmp_2_16595040_G_A 70 E>K No 1000Genomes
ENSVATH00266290 72 N>H No 1000Genomes
ENSVATH05686173 72 N>I No 1000Genomes
tmp_2_16595075_T_A 81 N>K No 1000Genomes
ENSVATH05686176 85 E>K No 1000Genomes
tmp_2_16595264_TTGAAAATTA_T 93 L>* No 1000Genomes
tmp_2_16595281_G_T 98 K>N No 1000Genomes
ENSVATH01969429 99 P>S No 1000Genomes
ENSVATH00266291 103 S>G No 1000Genomes
tmp_2_16595315_T_A 110 Y>N No 1000Genomes
tmp_2_16595318_A_C 111 N>H No 1000Genomes
ENSVATH05686177 115 I>M No 1000Genomes
ENSVATH13586964 121 M>I No 1000Genomes
tmp_2_16595388_C_A 134 P>H No 1000Genomes
tmp_2_16595393_A_C 136 N>H No 1000Genomes
ENSVATH01969431 138 E>D No 1000Genomes
ENSVATH01969430 138 E>G No 1000Genomes
ENSVATH07913712 139 L>I No 1000Genomes
ENSVATH13586985 142 P>S No 1000Genomes
ENSVATH05686178 143 L>I No 1000Genomes
ENSVATH05686178 143 L>V No 1000Genomes
tmp_2_16595426_G_T 147 V>F No 1000Genomes
ENSVATH01969434 152 G>E No 1000Genomes
ENSVATH01969433 152 G>R No 1000Genomes
ENSVATH05686179 154 S>I No 1000Genomes
ENSVATH05686179 154 S>N No 1000Genomes
tmp_2_16595452_A_G 155 I>M No 1000Genomes
ENSVATH14599585 156 E>K No 1000Genomes
tmp_2_16595463_G_A 159 C>Y No 1000Genomes
tmp_2_16595465_C_A 160 Q>K No 1000Genomes
ENSVATH01969436 161 A>T No 1000Genomes
tmp_2_16595469_C_T 161 A>V No 1000Genomes
tmp_2_16595471_T_G 162 Y>D No 1000Genomes
ENSVATH13586986 171 L>F No 1000Genomes
ENSVATH05686180 172 T>A No 1000Genomes
ENSVATH05686181 177 Q>P No 1000Genomes
ENSVATH00266292 201 R>S No 1000Genomes
tmp_2_16595702_G_C 209 A>P No 1000Genomes
tmp_2_16595773_G_T 232 K>N No 1000Genomes
tmp_2_16595782_C_G 235 N>K No 1000Genomes

No associated diseases with O22288

No regional properties for O22288

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O22288

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFAWCVRRS ASKLASACGQ ARSISAVVNR PSLALNPSPL SPFVSRGFLY TMAVDKLSSE
70 80 90 100 110 120
QTLHLVIDSE LNSALQTDDP NLNEEMAPGS FPLKIRDKPG DQSVTLTAYY NDERIHVDVG
130 140 150 160 170 180
MPYLGDDVID VFGPNNDELS FPLVVTVIKK NGVSIEFTCQ AYADYIDLTD LTVHDYQYQM
190 200 210 220 230
GETDWPRFKN LDDNLKKAFH RYLATRLDAN ITKLLHKYMV SKIKREYLLW LKNVNKFVDG