O22259

PR
Gene name
ERF071
Protein name
Ethylene-responsive transcription factor ERF071
Names
AtERF71, Protein HYPOXIA RESPONSIVE ERF 2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G47520
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O22259

Entry ID Method Resolution Chain Position Source
AF-O22259-F1 Predicted AlphaFoldDB

13 variants for O22259

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05735720 38 E>G No 1000Genomes
tmp_2_19503241_T_A 56 R>W No 1000Genomes
tmp_2_19503233_C_T 58 W>* No 1000Genomes
tmp_2_19503196_C_T 71 G>S No 1000Genomes
tmp_2_19503169_T_G 80 K>Q No 1000Genomes
ENSVATH05735719 83 D>V No 1000Genomes
ENSVATH05735718 107 N>K No 1000Genomes
ENSVATH01998974
tmp_2_19503061_T_A
 116 T>S No 1000Genomes
ENSVATH13669112 118 P>Q No 1000Genomes
tmp_2_19503044_A_T 121 N>K No 1000Genomes
ENSVATH05735717 132 E>D No 1000Genomes
tmp_2_19503008_G_T 133 S>R No 1000Genomes
tmp_2_19502990_C_T 139 M>I No 1000Genomes

No associated diseases with O22259

No regional properties for O22259

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O22259

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific double-stranded DNA binding Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.

7 GO annotations of biological process

Name Definition
cellular response to hypoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
regulation of root development Any process that modulates the frequency, rate or extent of root development.
response to anoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
response to water deprivation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MCGGAIISDF IWSKSESEPS QLGSVSSRKK RKPVSVSEER DGKRERKNLY RGIRQRPWGK
70 80 90 100 110 120
WAAEIRDPSK GVRVWLGTFK TADEAARAYD VAAIKIRGRK AKLNFPNTQV EEEADTKPGG
130 140 150 160 170
NQNELISENQ VESLSEDLMA LEDYMRFYQI PVADDQSATD IGNLWSYQDS N