O18823

PR
Gene name
AOAH
Protein name
Acyloxyacyl hydrolase
Names
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
ocu:100008662
EC number
3.1.1.77: Carboxylic ester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for O18823

Entry ID Method Resolution Chain Position Source
5W7A X-ray 230 A PDB
5W7B X-ray 190 A PDB
AF-O18823-F1 Predicted AlphaFoldDB

No variants for O18823

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O18823

No associated diseases with O18823

2 regional properties for O18823

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 42 - 158 IPR001789
domain Myb domain, plants 223 - 277 IPR006447

Functions

Description
EC Number 3.1.1.77 Carboxylic ester hydrolases
Subcellular Localization
  • Secreted
  • Cytoplasmic vesicle
  • Detected in urine
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
acyloxyacyl hydrolase activity Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.
calcium ion binding Binding to a calcium ion (Ca2+).

2 GO annotations of biological process

Name Definition
fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
lipopolysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKSPWRILVV SPLLLLPLHS STSRAHDNQP GTIRSDHYTC VGCVLVVSVI EQLAQVHNST
70 80 90 100 110 120
VQASMERLCS YLPEEWVLKT ACYMMVHVFG ADIIKLFDKD VNADVVCHTL EFCKQEPGQP
130 140 150 160 170 180
LCHLYPLPKE SWKFTLEKAR HIVKQSPIMK YTRSGAGICS LPFLAKICQK IKLAIKNSVP
190 200 210 220 230 240
IKDVDSDKYS IFPTLRGYHW RGRDCNDSDK TVYPGRRPDN WDAHRDSNCN GIWGVDPKDG
250 260 270 280 290 300
IPYEKKFCEG SQPRGIILLG DSAGAHFHIP PEWLTVSQMS VNSFLNLPTA VTNELDWPQL
310 320 330 340 350 360
SGTTGFLDSA SKIKENSIYL RLRKRNRCNH RDYQNISKNG ASSRNVKSLI ESLSRNQLLD
370 380 390 400 410 420
HPAIVIYAMI GNDVCNGRKT DPVSAMTTPE QLYANVLKML EALNSHLPTG SHVILYGLAH
430 440 450 460 470 480
GAFLWDTLHS RYHPLGQLNK DVTYTQLYSF LGCLQVSPCP GWMSANETLR ALTSERAQQL
490 500 510 520 530 540
SETLRKIAAS KKFTNFNLFY LDFAFQEVVE EWQKMGGQPW ELIEAVDGFH PNEVALLLFA
550 560 570
DQLWEKVQRQ WPDVLGKENP FNPQIEEVFG DQGGH