Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O17319
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O17319-F1 | Predicted | AlphaFoldDB |
No variants for O17319
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O17319 | |||||
No associated diseases with O17319
No regional properties for O17319
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O17319 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEKESPSPQ | HKKDEVVDDT | EQETKDSEDD | ATKKMKIKEG | SKFTMNSILS | PLESLARVQQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QLLKMAAAQS | GFGGNGSGGN | GANGFPYPAR | FATNCFSGPF | PGYNGSQNWY | NGNDARFAAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AALLPCAIDP | VRSAINHQFS | MSQRRKRRVL | FSQAQVYELE | RRFKQAKYLT | APEREQLANS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IRLTPTQVKI | WFQNHRYKCK | RQEKEKAMSG | LGHGDDGCSP | PPGDDDDDDD | KYSIEMDDKD |
| 250 | 260 | 270 | 280 | 290 | |
| DEEEDGAKPM | LKSNGVFGLP | YPSPANAAAA | AAAAAFNFQF | GAQGPNPAYF | MRW |