O16962

PR
Gene name
nhr-55 (T01G6.7)
Protein name
Nuclear hormone receptor family member nhr-55
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_T01G6.7
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O16962

Entry ID Method Resolution Chain Position Source
AF-O16962-F1 Predicted AlphaFoldDB

No variants for O16962

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O16962

No associated diseases with O16962

17 regional properties for O16962

Type Name Position InterPro Accession
domain SNF2, N-terminal 744 - 1024 IPR000330
domain Chromo/chromo shadow domain 499 - 586 IPR000953-1
domain Chromo/chromo shadow domain 620 - 677 IPR000953-2
domain Helicase, C-terminal 1051 - 1203 IPR001650
domain Zinc finger, PHD-type 372 - 415 IPR001965-1
domain Zinc finger, PHD-type 451 - 494 IPR001965-2
conserved_site DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site 868 - 877 IPR002464
domain CHD subfamily II, SANT-like domain 1366 - 1523 IPR009462
domain Domain of unknown function DUF1087 1289 - 1353 IPR009463
domain CHD, C-terminal 2 1726 - 1871 IPR012957
domain CHD, N-terminal 164 - 217 IPR012958
domain Helicase superfamily 1/2, ATP-binding domain 722 - 934 IPR014001
conserved_site Zinc finger, PHD-type, conserved site 373 - 414 IPR019786-1
conserved_site Zinc finger, PHD-type, conserved site 452 - 493 IPR019786-2
domain Zinc finger, PHD-finger 370 - 417 IPR019787-1
domain Zinc finger, PHD-finger 449 - 496 IPR019787-2
domain Chromo domain 623 - 673 IPR023780

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding Binding to a zinc ion (Zn).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O17025 nhr-90 Nuclear hormone receptor family member nhr-90 Caenorhabditis elegans PR
Q9TXJ1 nhr-59 Nuclear hormone receptor family member nhr-59 Caenorhabditis elegans PR
O16662 nhr-115 Nuclear hormone receptor family member nhr-115 Caenorhabditis elegans PR
O45460 nhr-54 Nuclear hormone receptor family member nhr-54 Caenorhabditis elegans PR
Q95X91 nhr-96 Nuclear hormone receptor family member nhr-96 Caenorhabditis elegans PR
O18048 nhr-213 Nuclear hormone receptor family member nhr-213 Caenorhabditis elegans PR
Q966I0 nhr-98 Nuclear hormone receptor family member nhr-98 Caenorhabditis elegans PR
10 20 30 40 50 60
MNSPSSSSSF CSSSSSPSSL VLYSPDTCQV CGQKSHGKHF GAVTCRACAA FFRRCGSANN
70 80 90 100 110 120
FKPCRRNMNC EFLKNGWFNC KPCRLKKCQD VGMTIENFQF DRDSFSPKKA KIALENFHNQ
130 140 150 160 170 180
VPFSIATFTG RSNLIVISAP TEEECIPKCY IDVQFLIDKL SNVLKEGPEV PLHTPNALEK
190 200 210 220 230 240
LALGLQIIRG RKRELKLITK LGKEETLGLW QDDMMKVAKW LTYFDDFQQL SHRMRSEMLK
250 260 270 280 290 300
GMWKVWSRLE TLALTAMGRR LMICQKDMIM THTEKEQVMA HPKQIEVDIS WCSRYTLEQL
310 320 330 340 350 360
RFFADSDLDD RNEQVIQAMM ELQPTDVELS YMMCQACLHY AGKRYQGEVL EIAERFQETL
370 380 390 400 410 420
SNHLHDYYVN RMNMPQYSMR VANLMKINNH IQLDIYRGRV KYDLARVFDV FYLEFSHPEV
FIDL