O14448
Gene name |
SUM1 (RPKA, MGG_07335) |
Protein name |
cAMP-dependent protein kinase regulatory subunit |
Names |
PKA regulatory subunit |
Species |
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) |
KEGG Pathway |
mgr:MGG_07335 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14448
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14448-F1 | Predicted | AlphaFoldDB |
No variants for O14448
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O14448 | |||||
No associated diseases with O14448
6 regional properties for O14448
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cyclic nucleotide-binding domain | 130 - 260 | IPR000595-1 |
| domain | Cyclic nucleotide-binding domain | 262 - 380 | IPR000595-2 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 158 - 174 | IPR018488-1 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 206 - 223 | IPR018488-2 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 289 - 305 | IPR018488-3 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 327 - 344 | IPR018488-4 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cAMP-dependent protein kinase complex | An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cAMP binding | Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate). |
| cAMP-dependent protein kinase regulator activity | Modulation of the activity of the enzyme cAMP-dependent protein kinase. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of protein phosphorylation | Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSASGFTSPF | GANSNPFGSP | EERRGVAGSI | QPVLEEEEAD | GIGSEPISFK | SPGFRAPFGG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDANSEGPPS | SRPQNPDGYP | AQYNFARRTS | VSAESLKPIA | DSYDNWTPPF | HPKSAEQLDR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LKKAIQGNFL | FSHLDDEQSA | QILGALVEKP | IPAKDIKVIV | QGDAGDYFYV | VEKGKFSVHV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NSSGVMQAGT | QGLGDHVGTI | EAGGSFGELA | LMYNAPRAAT | VMSAEPNCVL | WALDRVTFRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ILMESTFSRR | RMYENFLEEV | PILSTLTAYE | RSKIADALET | QKYPPGTVVI | KEGDPGEDFY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLECGEAEAF | KAGIDQPVKL | YKKGDFFGEL | ALLNDAPRAA | SVVSKTEVKV | AALGKSAFQR |
| 370 | 380 | ||||
| LLGPVEPIMR | RTRYDAIKTG | VEEMDPLQAA |