O14408

PR
Gene name
Protein name
Calcium/calmodulin-dependent protein kinase
Names
Species
Metarhizium anisopliae (Entomophthora anisopliae)
KEGG Pathway
EC number
2.7.11.17: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

283-382 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

181-185 (Activation loop from InterPro)

Target domain

23-278 (Protein kinase domain)

Relief mechanism

Assay

162-170 (Activation loop from InterPro)

Target domain

23-278 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for O14408

Entry ID Method Resolution Chain Position Source
AF-O14408-F1 Predicted AlphaFoldDB

No variants for O14408

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O14408

No associated diseases with O14408

2 regional properties for O14408

Type Name Position InterPro Accession
domain Rotavirus VP4 helical domain 484 - 775 IPR035329
domain Rotavirus VP4, membrane interaction domain 249 - 473 IPR035330

Functions

Description
EC Number 2.7.11.17 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
calmodulin-dependent protein kinase activity Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFAGMLNRL HGQPESYDKK SKYKFGRTLG AGTYGVVREA DGPSGKVAIK IILKKNVKGN
70 80 90 100 110 120
EKMVYAELDM LQRLTHPHIV KFVDWFESRD KFYIVTQLAT GGELFDRICD QGKFTEVDAS
130 140 150 160 170 180
QTIRQIMTAV DYLHDNDVVH RDLKPENLLY VTRDPDSDLV LADFGITKTL DIKEETLTTM
190 200 210 220 230 240
AGSFGYAAPE VMEQKGHGKP VDMWSMGVIT YTLLCGYSPF RSENLRDLLR ECTAAPVPFH
250 260 270 280 290 300
ERYWKDVSQD AKDFILVLLV PEPEKRWTSK EALGHIWLSG KNATDHNLLP ELEAYRRRAR
310 320 330 340 350 360
LRRVIEIVKL QNRIAKLKEH EEDPSESDMG DAQGASDNHK GDGSRLHALG LFAVREAKQK
370 380
QESLQVEEEL EKESRRRSFS NA