O14354
Gene name |
mgm101 (SPBC30D10.08) |
Protein name |
Mitochondrial genome maintenance protein mgm101 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC30D10.08 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14354
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14354-F1 | Predicted | AlphaFoldDB |
No variants for O14354
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O14354 | |||||
No associated diseases with O14354
No regional properties for O14354
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O14354 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial chromosome | A chromosome found in the mitochondrion of a eukaryotic cell. |
| mitochondrial nucleoid | The region of a mitochondrion to which the DNA is confined. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| single-stranded DNA binding | Binding to single-stranded DNA. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| interstrand cross-link repair | Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. |
| mitochondrial DNA repair | The process of restoring mitochondrial DNA after damage. |
| mitochondrial genome maintenance | The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. |
| recombinational repair | A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQTMLGKPAL | QYFGKLSRYL | YKNGEPINIW | VYSRNSSFSV | IPKNGLLSPK | ITQRFYQNSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IQYQKDKNIY | EPKENLEEKE | LSEGFLDESR | LEIPEAGHNW | EKSFFGLSSQ | PFSKEICDLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TAPLEVDDIE | IKPDGILYLP | EIKYRRILNK | AFGPGGWGLA | PRGNTNVTSK | SVSREYALVC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HGRLVSVARG | EQTYFDPEGI | ATASEGCKSN | ALMRCCKDLG | VASELWDPRY | IRVFKRENCV |
| 250 | 260 | ||||
| EVFVENVLTK | KRRKLWRRKE | DKFSYPYKEV |