Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O14297

Entry ID Method Resolution Chain Position Source
AF-O14297-F1 Predicted AlphaFoldDB

4 variants for O14297

Variant ID(s) Position Change Description Diseaes Association Provenance
I_4471002_G_A 108 E>K No Jeffares_SNPs
I_4471209_G_A 177 V>I No Jeffares_SNPs
I_4471252_C_T 191 T>I No Jeffares_SNPs
I_4471263_A_T 195 M>L No Jeffares_SNPs

No associated diseases with O14297

1 regional properties for O14297

Type Name Position InterPro Accession
domain NADH:ubiquinone oxidoreductase intermediate-associated protein 30 5 - 177 IPR013857

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
NADH dehydrogenase complex assembly The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.
protein-containing complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLVLFGQPEN WHEQDFRAVD DRVRGGSSIS HLTEEKDSDG KSRAKFWGTL DTKTLGGAGF
70 80 90 100 110 120
CSQATNIKDR TWNLKEFKGI ELDIAKSDSY KYTFIIKDCH QDWETSDEKS SLSYEYDFTP
130 140 150 160 170 180
IYSKEDQVVS IPFSEFKPTY RGRPVEGAPE LDVSKITQFS IMIRSFFNSQ SGDYELVLNS
190 200 210
IRAIPKNVPF TTHKMSNEKQ RLFDDYEKEI AGGSWCICQ