O14225
Gene name |
tom20 (SPAC6F12.07) |
Protein name |
Mitochondrial import receptor subunit tom20 |
Names |
Mitochondrial 20 kDa outer membrane protein, Translocase of outer membrane 20 kDa subunit |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC6F12.07 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14225
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14225-F1 | Predicted | AlphaFoldDB |
No variants for O14225
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O14225 | |||||
No associated diseases with O14225
No regional properties for O14225
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O14225 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial outer membrane | The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane translocase complex | A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mitochondrion targeting sequence binding | Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into mitochondrial matrix | The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. |
| tRNA import into mitochondrion | The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRRSVIIGSL | LATAAVGYAI | YFDYKRRNDP | HFRKTLKRRY | KKVHEAKKQE | EKLATKKFDI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TVEEALQVVA | STPVPSSAEE | KELFFMQQVA | RGEQLFQQQP | DNIKESAACF | YSALKVYPQP |
| 130 | 140 | 150 | |||
| VELFAIYERT | VPEPIMNLLR | AMQAKESIPS | VE |