O14158
Gene name |
SPAC4A8.06c |
Protein name |
AB hydrolase superfamily protein C4A8.06c |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC4A8.06c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14158
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14158-F1 | Predicted | AlphaFoldDB |
7 variants for O14158
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_2554990_C_T | 254 | V>I | No | Jeffares_SNPs | |
| I_2554823_T_C | 309 | I>M | No | Jeffares_SNPs | |
| I_2554801_T_C | 317 | K>E | No | Jeffares_SNPs | |
| I_2554268_A_T | 494 | D>E | No | Jeffares_SNPs | |
| I_2554147_A_G | 535 | Y>H | No | Jeffares_SNPs | |
| I_2554096_T_C | 552 | K>E | No | Jeffares_SNPs | |
| I_2554051_C_T | 567 | V>I | No | Jeffares_SNPs |
No associated diseases with O14158
2 regional properties for O14158
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha/beta hydrolase fold-3 | 141 - 254 | IPR013094-1 |
| domain | Alpha/beta hydrolase fold-3 | 346 - 427 | IPR013094-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| triglyceride lipase activity | Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLKKEQLTVE | SINDGISKTF | SQAFRFLAHH | ELRKNRTFML | DLGVSILKKF | LIDSRDYKVE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVQDFCSRSL | TDEFKFKFTS | QPIDSKSESD | SASYIRNYLG | PEGIKQFGGS | NWWLYRKSPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KSWWIERRHH | IRHNLKCDKV | IFYVHGGAHY | LSTVRTNAYH | IQRHTAALGA | RTFAPDLRLA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PQFPFPCSLH | DVLSSYLYLL | KSTKPENIIF | MGDSSGAGLI | VASLVLIRDS | KLPLPAGVVY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DSPWVDLTHS | LPSVVADDAA | DYIPSEGFHH | RASRYWPITN | LDSFSTISEK | ELLNYSKKQE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LTNFIENSIR | KKIQTIKNLI | PVLQEMDKEH | ARIDFDNVDS | RLDPNILTTF | PFQVQFYTSN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ANLKHPLISP | IFTENLGGLP | PSLVLGGSGE | RLRDEIVYIA | HKMNTDVYNG | KRTKVRLEMY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DDCCHVVTAL | PFVKEAGIMV | RRAANFAYWC | LKQHDSSFVS | PNKHLDGNPS | HANEDMVRLR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ISRNGEERLM | EPKDEIQCLN | LPKSALGTIQ | VKALIRWIDV | ELILLSKDTK | KPARYFAEFK |
| 550 | 560 | 570 | |||
| HADLNGYLVK | PKEYTMEGEN | PPLSALVANC | KISPEKKQ |