O14078

PR
Gene name
SPAC2E11.13c (SPACUNK4.13c)
Protein name
Obg-like ATPase homolog
Names
OLA1 homolog
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPACUNK4.13c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O14078

Entry ID Method Resolution Chain Position Source
AF-O14078-F1 Predicted AlphaFoldDB

6 variants for O14078

Variant ID(s) Position Change Description Diseaes Association Provenance
I_2885859_C_A 121 T>K No Jeffares_SNPs
I_2885885_C_T 130 L>F No Jeffares_SNPs
I_2886140_A_G 215 K>E No Jeffares_SNPs
I_2886147_G_A 217 R>H No Jeffares_SNPs
I_2886183_T_C 229 I>T No Jeffares_SNPs
I_2886614_A_G 373 K>E No Jeffares_SNPs

No associated diseases with O14078

5 regional properties for O14078

Type Name Position InterPro Accession
domain TGS 322 - 405 IPR004095
domain GTP binding domain 47 - 161 IPR006073
domain YchF, C-terminal domain 321 - 405 IPR013029
domain OBG-type guanine nucleotide-binding (G) domain 46 - 301 IPR031167
domain YchF, N-terminal 48 - 321 IPR041706

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GTP binding Binding to GTP, guanosine triphosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRGIVTRIVL STQKCLPSVN CTRRYYSKQK DISIVRQRLG RPGNHLKIGI VGMPNIGKST
70 80 90 100 110 120
LFQILTKTNL GNPANYPFAT IDPVHAKAPV LDSQYELLCE IYQPKTRIPA QLTIYDTAGL
130 140 150 160 170 180
TRNSSKGEGL GNAFLSNIRS VDALFQLVRA FPEAQVPHVE KSVDPVRDLQ IIQEELLLKD
190 200 210 220 230 240
AEFLESYLKK EGRSPKTCAK ALDTARRALE VVLGKGRQIS KAEWNDEQIP ILNSLNLLTA
250 260 270 280 290 300
KPVVYLVNMD QDDYLSDEQE ALKGIKEWVE KNSFGDQVIP LSVLFEEQLF MLTPEEAAQE
310 320 330 340 350 360
CASLGKNSQL SEIICAGYSA LNLIHYFTAS EKIVQAWTIA DGSKAPDAAG IIHSDFKKKF
370 380 390 400
VAGEVIKFSD FEKYKSVDAC KSVGKCKTKG KDYTVEPGDI IFWKIAR