O14059
Gene name |
SPCC1672.01 |
Protein name |
Probable histidinol-phosphatase |
Names |
HolPase |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
|
EC number |
3.1.3.15: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14059
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14059-F1 | Predicted | AlphaFoldDB |
No variants for O14059
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O14059 | |||||
No associated diseases with O14059
1 regional properties for O14059
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PHP domain | 6 - 214 | IPR004013 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.15 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| histidinol-phosphatase activity | Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine biosynthetic process | The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPISSHSHSG | QFCLHAQGKL | EDVIQEAIQQ | GFQSFSFTEH | TPRDRVEDLY | PEELHLQPED |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LFKTFDEYVN | EARRLKQNYG | DQINILIGAE | TEYIRPESVE | LLKSLNTKYN | LDYFVGSVHH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VNSIPIDFSP | ELWQKALQHV | GNNPEQLFID | YFEHQYDLMQ | RLHPLVIGHF | DLICLFAPED |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AKEVFKNSKS | VWELIQRNIK | YAVSYGGIFE | INTSAFRKGW | KTAYPQQRLL | ELMVEQGAQL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLSDDSHGPH | QVGLNYHLAK | SYLDKCGITS | LCMIEKGPDG | NGTVVKNVTV | DNVWSKFVGT |
| NGITNT |