O14048

PR
Gene name
ubx2 (SPAC2C4.15c)
Protein name
UBX domain-containing protein 2
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC2C4.15c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

16-174 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O14048

Entry ID Method Resolution Chain Position Source
AF-O14048-F1 Predicted AlphaFoldDB

12 variants for O14048

Variant ID(s) Position Change Description Diseaes Association Provenance
I_4286182_C_G 7 S>T No Jeffares_SNPs
I_4286038_A_G 55 I>T No Jeffares_SNPs
I_4285750_G_C 151 P>R No Jeffares_SNPs
I_4285732_G_C 157 S>C No Jeffares_SNPs
I_4285727_G_T 159 L>I No Jeffares_SNPs
I_4285547_G_A 219 P>S No Jeffares_SNPs
I_4285366_T_C 279 N>S No Jeffares_SNPs
I_4285273_T_C 310 N>S No Jeffares_SNPs
I_4285100_G_T 368 R>S No Jeffares_SNPs
I_4285090_G_C 371 S>C No Jeffares_SNPs
I_4285043_C_T 387 A>T No Jeffares_SNPs
I_4284986_T_C 406 T>A No Jeffares_SNPs

No associated diseases with O14048

2 regional properties for O14048

Type Name Position InterPro Accession
domain Transglutaminase-like 200 - 255 IPR002931
domain Rad4/PNGase transglutaminase-like fold 232 - 291 IPR018325

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
ubiquitin binding Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.

1 GO annotations of biological process

Name Definition
proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDGDEASLVA NFCAITNSTP EKAQEYLSVA DGDLSTAITL FFESGGVTDV QSSYIEAPSQ
70 80 90 100 110 120
TEPVEEIRAP IAPTREVLVD PLADMSAGTS IMGNNFGFGG FPRMNRRQRR RMGIFDQSPS
130 140 150 160 170 180
QIPFPSSNTE DSSEESDSSS RASRLAKLFR PPYDIISNLS LDEARIEASS QKRWILVNLQ
190 200 210 220 230 240
TSTSFECQVL NRDLWKDESV KEVIRAHFLF LQLLDDEEPG MEFKRFYPVR STPHIAILDP
250 260 270 280 290 300
RTGERVKEWS KSFTPADFVI ALNDFLEGCT LDETSGRKNP LGAKSQKPVE AMSEDEQMHK
310 320 330 340 350 360
AIAASLGNGN STTESQGESS SQQAESHGVA DDTVHKIDSA ECDAEEPSPG PNVTRIQIRM
370 380 390 400 410 420
PNGARFIRRF SLTDPVSKVY AYVKGVAEGA DKQPFSLTFQ RKSLWTSLDS TIKEAGIQNT
ALQFEFQ