O13984
Gene name |
SPAC26H5.02c |
Protein name |
ATPase WRNIP1 homolog C26H5.02c |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC26H5.02c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13984
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13984-F1 | Predicted | AlphaFoldDB |
10 variants for O13984
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_4118925_T_C | 17 | T>A | No | Jeffares_SNPs | |
| I_4118832_A_T | 48 | Y>N | No | Jeffares_SNPs | |
| I_4118826_G_A | 50 | H>Y | No | Jeffares_SNPs | |
| I_4118795_T_C | 60 | Q>R | No | Jeffares_SNPs | |
| I_4118762_C_T | 71 | S>N | No | Jeffares_SNPs | |
| I_4118690_A_G | 95 | L>P | No | Jeffares_SNPs | |
| I_4117572_T_G | 424 | S>R | No | Jeffares_SNPs | |
| I_4117340_T_A | 488 | I>L | No | Jeffares_SNPs | |
| I_4117317_T_A | 495 | E>D | No | Jeffares_SNPs | |
| I_4117303_T_C | 500 | K>R | No | Jeffares_SNPs |
No associated diseases with O13984
5 regional properties for O13984
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| enzyme activator activity | Binds to and increases the activity of an enzyme. |
| metal ion binding | Binding to a metal ion. |
| single-stranded DNA helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA synthesis involved in DNA repair | Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template. |
| DNA-templated DNA replication | A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. |
| Okazaki fragment processing involved in mitotic DNA replication | Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication. |
| regulation of DNA repair | Any process that modulates the frequency, rate or extent of DNA repair. |
| UV-damage excision repair | A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGPDHVQCP | VCAKTVTMND | INPHLDSHYS | DSSGPSKPVS | PFFKKERYKH | HLETNVSSHQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SATKFIEPEP | SPTKKTKLTR | RDTRPLAERA | RPKSLDEYVG | QEELVGERGI | IRNLIEQDRC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NSMILWGSAG | TGKTTLARLI | AVTTKSRFIE | ISATSTTVAD | CRKIFEDSQN | YLTLTGRKTI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IFLDEVHRFN | RAQQDIFLPM | VEKGLVTLIG | ATTENPSFRL | NSALISRCPV | FVLKKLTRDN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VKKILNHACL | LESERLGSSM | PNVETSIIDY | ISAITDGDAR | MALNALEMSI | GMLRQGPLSL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EDIKDKLVRS | SALYDRVGDV | HYDTISAFHK | SVRGSDVDAT | LYYLGRMLES | GEDPLYVARR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MVRIASEDIG | IADNSMLPLA | SSTFTAVQQV | GMPEADVILA | HCAVALALAP | KSVDVYRSYN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AVKSFLSSHP | DAGRAEIPMH | IRNAPTNLMK | QLGYHKGYKY | NPDYKDGLVM | QEYLPDSIKG |
| 490 | 500 | ||||
| TKFYKLPIEL | KEDEEIKNLK | TDTK |