O13787
Gene name |
sec62 (SPAC17G6.09) |
Protein name |
Translocation protein sec62 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC17G6.09 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13787
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13787-F1 | Predicted | AlphaFoldDB |
4 variants for O13787
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_3604134_T_C | 15 | C>R | No | Jeffares_SNPs | |
| I_3604233_G_T | 48 | V>L | No | Jeffares_SNPs | |
| I_3604633_T_C | 181 | L>S | No | Jeffares_SNPs | |
| I_3604831_C_G | 247 | T>S | No | Jeffares_SNPs |
No associated diseases with O13787
No regional properties for O13787
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O13787 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of endoplasmic reticulum membrane | The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| Sec62/Sec63 complex | A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| post-translational protein targeting to membrane, translocation | The process in which a protein translocates through the ER membrane posttranslationally. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSSNVPVLK | DEDKCKFSMR | FTNFLKSRPE | LKTKPAILNG | KRVYYFRVKR | VLRFLTSEAY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TPKKYKGFPE | ISSREEAIEV | LKLLIMNSML | VRVDKLPPKQ | RKQKLVELQI | NRNQDFQDDM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HYVWLYEPLP | KRVMALAVLF | ALVVLALVLF | PLWPMFMRKG | AWYLSMGGLG | VIGLFFVLVI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRFFLFCITA | VIVRPGIWLF | PNLLADVGFC | DSFKPLWSWH | NSKSEVKKTR | KSKKLSKKAT |
| 250 | 260 | 270 | |||
| SPAASATPEK | SSTSTTSLKN | LRHRNPTVEE | VSE |