O13785
Gene name |
use1 (SPAC17G6.07c) |
Protein name |
Protein transport protein use1 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC17G6.07c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13785
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13785-F1 | Predicted | AlphaFoldDB |
3 variants for O13785
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_3600680_T_C | 59 | K>R | No | Jeffares_SNPs | |
| I_3600506_G_T | 117 | A>D | No | Jeffares_SNPs | |
| I_3600252_T_G | 202 | I>L | No | Jeffares_SNPs |
No associated diseases with O13785
No regional properties for O13785
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O13785 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| SNARE complex | A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| SNAP receptor activity | Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKDLISRLE | RQFKLKRDEF | QDPLELLKFE | KNLDYARKLL | WEEGKCQLDK | VAEPQGLSKR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IMDLQGRIYD | LNVTMEKKLK | IEEKKIKSKQ | EKEIAHALQS | IQERELRERQ | QMSNVEASNA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QLLTNQRSMQ | TEISESLLHL | ASVLKENALS | FTNALVTDNQ | VVERTGSLLD | KNAHSLRHAN |
| 190 | 200 | 210 | 220 | ||
| HGVQSYSKSK | RLSFWLQLGM | IIAVVVSFIV | MIFILQFTKN | QN |