O13741
Gene name |
nop12 (SPAC16E8.06c) |
Protein name |
Nucleolar protein 12 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC16E8.06c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13741
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13741-F1 | Predicted | AlphaFoldDB |
6 variants for O13741
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_3509562_G_A | 134 | S>L | No | Jeffares_SNPs | |
| I_3509517_C_T | 149 | R>H | No | Jeffares_SNPs | |
| I_3509089_C_T | 292 | D>N | No | Jeffares_SNPs | |
| I_3508920_G_A | 348 | S>F | No | Jeffares_SNPs | |
| I_3508902_A_G | 354 | I>T | No | Jeffares_SNPs | |
| I_3508802_C_A | 387 | L>F | No | Jeffares_SNPs |
No associated diseases with O13741
5 regional properties for O13741
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pumilio RNA-binding repeat | 114 - 149 | IPR001313-1 |
| repeat | Pumilio RNA-binding repeat | 150 - 187 | IPR001313-2 |
| repeat | Pumilio RNA-binding repeat | 355 - 390 | IPR001313-3 |
| repeat | Pumilio RNA-binding repeat | 538 - 575 | IPR001313-4 |
| repeat | Pumilio RNA-binding repeat | 576 - 613 | IPR001313-5 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGETNSSLDN | ENTSFVGKLS | SSSNVDPTLN | LLFSQSKPIP | KPVAKETTVL | TKKDVEVEEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NGVEEAAETI | ESDTKEVQNI | KPKSKKKKKK | LNDSSDDIEG | KYFEELLAEE | DEEKDKDSAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LINDEEDKSP | AKQSVLEERT | SQEDVKSERE | VAEKLANELE | KSDKTVFVNN | LPARVVTNKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DYKDLTKHFR | QFGAVDSIRF | RSLAFSEAIP | RKVAFFEKKF | HSERDTVNAY | IVFRDSSSAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SALSLNGTMF | MDRHLRVDSV | SHPMPQDTKR | CVFVGNLAFE | AEEEPLWRYF | GDCGSIDYVR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IVRDPKTNLG | KGFAYIQFKD | TMGVDKALLL | NEKKMPEGRT | LRIMRAKSTK | PKSITRSKRG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DEKTRTLQGR | ARKLIGKAGN | ALLQQELALE | GHRAKPGENP | LAKKKVNKKR | KERAAQWRNK |
| 430 | |||||
| KAESVGKKQK | TAAGKKDK |