O13725
Gene name |
mug182 (SPAC15A10.05c) |
Protein name |
NAD(P)H-hydrate epimerase |
Names |
Meiotically up-regulated gene 182 protein, NAD(P)HX epimerase |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC15A10.05c |
EC number |
5.1.99.6: Acting on other compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13725
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13725-F1 | Predicted | AlphaFoldDB |
3 variants for O13725
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_3686118_T_C | 152 | E>G | No | Jeffares_SNPs | |
| I_3685851_A_G | 213 | V>A | No | Jeffares_SNPs | |
| I_3685818_G_T | 224 | P>H | No | Jeffares_SNPs |
No associated diseases with O13725
1 regional properties for O13725
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | YjeF N-terminal domain | 7 - 223 | IPR004443 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.1.99.6 | Acting on other compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| NADHX epimerase activity | Catalysis of the reaction: (R)-NADHX = (S)-NADHX. |
| NADPHX epimerase activity | Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX. |
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| nicotinamide nucleotide metabolic process | The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSISCLSASA | AKALDAELMS | AGAFSIDQLM | ELAGLSVSQA | VYREYPPSQY | SQVLICCGPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NNGGDGLVAA | RHLWQYGYKP | TVYYPKPSSP | ELYKRLCKQL | DDLDIPVVKS | HDSNHFSQLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RDSKLVVDSI | FGFSFKGPVR | DPFGSILAAI | VESKIKVLSV | DAPSSWEIDE | GPQKEGPLKD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FDPDTLISLT | APKPCSKFYK | GKHYLGGRFV | SKVITKKFNL | SLPPYPGIDQ | VVDITNKPLS |
| MV |