O13632
Gene name |
yvh1 (pi040, SPBC17A3.06) |
Protein name |
Tyrosine-protein phosphatase yvh1 |
Names |
PTPase yvh1 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC17A3.06 |
EC number |
3.1.3.48: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O13632
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O13632-F1 | Predicted | AlphaFoldDB |
No variants for O13632
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O13632 | |||||
No associated diseases with O13632
4 regional properties for O13632
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Dual specificity phosphatase, catalytic domain | 54 - 182 | IPR000340 |
| domain | Tyrosine-specific protein phosphatases domain | 104 - 168 | IPR000387 |
| domain | Protein-tyrosine phosphatase, catalytic | 89 - 215 | IPR003595 |
| domain | Dual specificity protein phosphatase domain | 45 - 187 | IPR020422 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.48 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein tyrosine phosphatase activity | Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. |
| protein tyrosine/serine/threonine phosphatase activity | Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| protein dephosphorylation | The process of removing one or more phosphoric residues from a protein. |
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
| signaling | The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNKSAWQPQ | FDEIHSSVQE | AEGFLQSSND | VQKAIDEVHY | PDSLNDLSEI | SKNLYISSWK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TASELVSTSD | KGIDYTLSAM | SINPNLSVPE | QQHLWLQIED | SSSQNILQYF | EKSNKFIAFA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSKNAKVLVH | CFAGISRSVT | LVAAYLMKEN | NWNTEEALSH | INERRSGISP | NANFLRQLRV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YFECNYQLDR | SLRPYRQWLF | RRYGDFAVLN | TRVPSEVAYA | ETVRARAGQL | ELRCKKCRFV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LASSDYLVSH | EPKDENNYSH | TRCTHYFLEP | IRWMQPELEL | GNLEGRFDCP | KCNSKIGSYK |
| 310 | 320 | ||||
| WQGLQCSCLQ | WVCPALSILQ | SRVDAVRKLG |