Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O13375

Entry ID Method Resolution Chain Position Source
AF-O13375-F1 Predicted AlphaFoldDB

No variants for O13375

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O13375

No associated diseases with O13375

1 regional properties for O13375

Type Name Position InterPro Accession
domain Membrane insertase YidC/Oxa/ALB, C-terminal 105 - 293 IPR028055

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGVANTSLRY SAFNFSLGRR FKSTSETLND LPETISEVQT QLPSIDQMTN ATADIVEQAS
70 80 90 100 110 120
HSVGELSTHI GYLNSIGLAQ TWHWPADIIQ HALEYVHVYT GLPWWGTICT VTILVRLLMF
130 140 150 160 170 180
PIYVKSSDTI AKNSRIKPQM DKVTKELMAT TDLAEGQKIA VRRRKLLSEN GIKNRWLAAP
190 200 210 220 230 240
MLQLPIAIGF FNALRSMANF PVDGFANQGI LWFHDLTLSD PYLGLQFITA AVLMSFSRLG
250 260 270 280 290 300
GETGAQQFSG PMKRFFIILP LVSIPATMNL STSVVLYFAI NGTFSVLQTL VLRNKWFRKK
310 320 330 340 350 360
LNIAEVVQHP PDPTKENSGI FAAIKENMNT ARERSEKRKL MKEEEERVHE LIKKKRTNER
370
IRIIRRPELK K