O13289

PR
Gene name
CAT1 (CTA1, CAALFM_C106810WA, CaO19.13609, CaO19.6229)
Protein name
Peroxisomal catalase
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C106810WA
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O13289

Entry ID Method Resolution Chain Position Source
AF-O13289-F1 Predicted AlphaFoldDB

No variants for O13289

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O13289

No associated diseases with O13289

4 regional properties for O13289

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 332 - 340 IPR002226
domain Catalase immune-responsive domain 419 - 477 IPR010582
domain Catalase core domain 6 - 392 IPR011614
active_site Catalase active site 42 - 58 IPR024708

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Peroxisome matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
fungal-type cell wall A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

3 GO annotations of biological process

Name Definition
biological process involved in interaction with host An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPTFTNSNG QPIPEPFATQ RVGQHGPLLL QDFNLIDSLA HFDRERIPER VVHAKGSGAY
70 80 90 100 110 120
GVFEVTDDIT DICAAKFLDT VGKKTRIFTR FSTVGGELGS ADTARDPRGF ATKFYTEEGN
130 140 150 160 170 180
LDLVYNNTPV FFIRDPSKFP HFIHTQKRNP ETHLKDANMF WDYLTSNEES IHQVMVLFSD
190 200 210 220 230 240
RGTPASYREM NGYSGHTYKW SNKKGEWFYV QVHFISDQGI KTLTNEEAGA LAGSNPDYAQ
250 260 270 280 290 300
EDLFKNIAAG NYPSWTAYIQ TMTEAEAKEA EFSVFDLTKV WPHKKYPLRR FGKFTLNENP
310 320 330 340 350 360
KNYFAEVEQA AFSPAHTVPY MEPSADPVLQ SRLFSYADTH RHRLGTNYTQ IPVNCPVTGA
370 380 390 400 410 420
VFNPHMRDGA MTVNGNLGSH PNYLASDKPV EFKQFSLQED QEVWNGAATP FHWKATPADF
430 440 450 460 470 480
KQAQELWKVL KRYPNQQEHL AHNIAVHAAG ADAAIQDRVF AYFGKVSQDL ADAIKKEVLE
LSPRK