O12948

PR
Gene name
opn1lw1
Protein name
Red-sensitive opsin
Names
Red cone photoreceptor pigment
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:399310
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

313-365 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O12948

Entry ID Method Resolution Chain Position Source
AF-O12948-F1 Predicted AlphaFoldDB

No variants for O12948

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O12948

No associated diseases with O12948

2 regional properties for O12948

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 69 - 321 IPR017452
binding_site Visual pigments (opsins) retinal binding site 305 - 321 IPR027430

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.

4 GO annotations of biological process

Name Definition
absorption of UV light The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
absorption of visible light The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASQLNEAIF AARRRNDDDD TTRSSVFTYT NSNNTRGPFE GPNYHIAPRW VYNLTSIWMI
70 80 90 100 110 120
FVVFASVFTN GLVIVATLKF KKLRHPLNWI LVNMAIADLG ETVIASTISV FNQIFGYFIL
130 140 150 160 170 180
GHPMCVLEGF TVSTCGITAL WSLTVIAWER WFVVCKPFGN IKFDEKLAAT GIIFSWVWSA
190 200 210 220 230 240
GWCAPPMFGW SRFWPHGLKT SCGPDVFSGS SDPGVQSYML VLMITCCIIP LAIIILCYLH
250 260 270 280 290 300
VWWTIRQVAQ QQKESESTQK AEREVSRMVV VMIVAYIFCW GPYTFFACFA AFSPGYSFHP
310 320 330 340 350 360
LAAALPAYFA KSATIYNPII YVFMNRQFRN CIYQMFGKKV DDGSEVSSTS RTEVSSVSNS
SVSPA