O07025
Gene name |
fliI (HP_1420) |
Protein name |
Flagellum-specific ATP synthase |
Names |
|
Species |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
KEGG Pathway |
hpy:HP_1420 |
EC number |
7.1.2.2: Hydron translocation linked to the hydrolysis of a nucleoside triphosphate |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O07025
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O07025-F1 | Predicted | AlphaFoldDB |
No variants for O07025
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O07025 | |||||
No associated diseases with O07025
4 regional properties for O07025
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain | 144 - 353 | IPR000194 |
| domain | AAA+ ATPase domain | 156 - 337 | IPR003593 |
| active_site | ATPase, alpha/beta subunit, nucleotide-binding domain, active site | 344 - 353 | IPR020003 |
| domain | T3SS EscN ATPase, C-terminal | 361 - 431 | IPR040627 |
Functions
| Description | ||
|---|---|---|
| EC Number | 7.1.2.2 | Hydron translocation linked to the hydrolysis of a nucleoside triphosphate |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| proton-transporting ATP synthase complex, catalytic core F(1) | The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled. |
| type III protein secretion system complex | A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| proton-transporting ATP synthase activity, rotational mechanism | Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out). |
| proton-transporting ATPase activity, rotational mechanism | Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| bacterial-type flagellum organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. |
| protein secretion by the type III secretion system | The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPLKSLKNRL | NQHFDLSPRY | GSVKKIMPNI | VYADGFNPSV | GDVVKIEKSD | GSECVGMVVV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AEKEQFGFTP | FNFIEGARAG | DKVLFLKEGL | NFPVGRNLLG | RVLNPLGQVI | DNKGALDYER |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LAPVITTPIA | PLKRGLIDEI | FSVGVKSIDG | LLTCGKGQKL | GIFAGSGVGK | STLMGMITRG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CLAPIKVIAL | IGERGREIPE | FIEKNLKGDL | SSCVLVVATS | DDSPLMRKYG | AFCAMSVAEY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FKNQGLDVLF | IMDSVTRFAM | AQREIGLALG | EPPTSKGYPP | SALSLLPQLM | ERAGKEENKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SITAFFSVLV | EGDDLSDPIA | DQTRSILDGH | IVLSRELTDY | GIYPPINILN | SASRVAKDII |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SESQNLCARK | FRRLYALLKE | NEMLIRIGSY | QMGNDKELDE | AIKKKALMEQ | FLAQDENALQ |
| 430 | |||||
| PFETSFQQLE | EILR |