O06865
Gene name |
pepA (ampA, lap, Synpcc7942_1190, SEE0038) |
Protein name |
Probable cytosol aminopeptidase |
Names |
Leucine aminopeptidase, LAP, Leucyl aminopeptidase |
Species |
Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans R2) |
KEGG Pathway |
syf:Synpcc7942_1190 |
EC number |
3.4.11.1: Aminopeptidases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O06865
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O06865-F1 | Predicted | AlphaFoldDB |
No variants for O06865
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O06865 | |||||
No associated diseases with O06865
1 regional properties for O06865
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cytochrome f large domain | 45 - 200 | IPR024094 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.4.11.1 | Aminopeptidases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| manganese ion binding | Binding to a manganese ion (Mn). |
| metalloaminopeptidase activity | Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTFQAIATHP | QDWTGDTLAL | GLTTAAIGET | LSSELQKLDQ | QWNGVLQELI | SDSEFKAKLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETTTTRIGGS | IRKLILVGLG | ESPTTEDYRR | AAAAVAKQAR | SFKSQTLAIA | FPPSDDPAAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASAIVEGISL | ALYKDQRFKS | EPDTASGPSS | IELLGLAGQE | AAIARAEQVV | AGVELARQLV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAPANVVTPV | TMADTAQELA | AELGLELEIL | EADECEKRGM | GAFLGVAKAS | DLPPKFIHLT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YRPESTPRRK | LAIVGKGLTF | DSGGYNIKGA | GSGIEMMKTD | MGGAAATLGA | AKAIGLIKPD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VEVHFISAVT | ENMISGRGMH | PGDILTASNG | KTIEVNNTDA | EGRLTLADAL | VFADGLGVDA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IVDLATLTGA | CIIALGDDIA | GLWSPSDDLA | EQLLQAGKAA | GEKLWRLPLE | EPYLDGLKSP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VADYKNTGPR | AGGSITAALF | LKQFVKHPVW | AHLDVAGPVW | SDKEKHYNPA | GATGYGVRTL |
| VNWVLS |