O06825

PR
Gene name
Rv1433 (RVBD_1433, P425_01489)
Protein name
Probable L,D-transpeptidase 3
Names
LDT 3, Ldt(Mt3)
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
KEGG Pathway
mtv:RVBD_1433
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

34-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for O06825

Entry ID Method Resolution Chain Position Source
4K73 X-ray 165 A A 20-271 PDB
6D4K X-ray 132 A A 32-271 PDB
6D51 X-ray 183 A A 33-271 PDB
AF-O06825-F1 Predicted AlphaFoldDB

No variants for O06825

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O06825

No associated diseases with O06825

2 regional properties for O06825

Type Name Position InterPro Accession
domain L,D-transpeptidase catalytic domain 157 - 270 IPR005490
domain Bacterial Ig domain, transpeptidase-associated 37 - 116 IPR041280

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
peptidoglycan L,D-transpeptidase activity Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.

3 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
peptidoglycan-protein cross-linking The process of covalently linking peptidoglycan (murein) to proteins.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRAVFGCAIA VVGIAGSVVA GPADIHLVAA KQSYGFAVAS VLPTRGQVVG VAHPVVVTFS
70 80 90 100 110 120
APITNPANRH AAERAVEVKS TPAMTGKFEW LDNDVVQWVP DRFWPAHSTV ELSVGSLSSD
130 140 150 160 170 180
FKTGPAVVGV ASISQHTFTV SIDGVEEGPP PPLPAPHHRV HFGEDGVMPA SMGRPEYPTP
190 200 210 220 230 240
VGSYTVLSKE RSVIMDSSSV GIPVDDPDGY RLSVDYAVRI TSRGLYVHSA PWALPALGLE
250 260 270
NVSHGCISLS REDAEWYYNA VDIGDPVIVQ E