O05209

PR
Gene name
vat (Ta0840)
Protein name
VCP-like ATPase
Names
Species
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
KEGG Pathway
tac:Ta0840
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

137-208 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

8 structures for O05209

Entry ID Method Resolution Chain Position Source
1CZ4 NMR - A 1-183 PDB
1CZ5 NMR - A 1-183 PDB
5G4F EM 700 A A/B/C/D/E/P 1-726 PDB
5G4G EM 780 A A/B/C/D/E/F 6-726 PDB
5VC7 EM 390 A A/C/D/E/F/G 183-745 PDB
5VCA EM 390 A M/N/O/P/Q/R 183-745 PDB
7DBO X-ray 190 A A/B 1-91 PDB
AF-O05209-F1 Predicted AlphaFoldDB

No variants for O05209

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O05209

No associated diseases with O05209

10 regional properties for O05209

Type Name Position InterPro Accession
domain CDC48, N-terminal subdomain 8 - 93 IPR003338
domain AAA+ ATPase domain 223 - 359 IPR003593-1
domain AAA+ ATPase domain 500 - 637 IPR003593-2
domain ATPase, AAA-type, core 227 - 356 IPR003959-1
domain ATPase, AAA-type, core 505 - 634 IPR003959-2
conserved_site ATPase, AAA-type, conserved site 327 - 345 IPR003960-1
conserved_site ATPase, AAA-type, conserved site 605 - 623 IPR003960-2
domain CDC48, domain 2 111 - 179 IPR004201
domain AAA ATPase, AAA+ lid domain 387 - 422 IPR041569-1
domain AAA ATPase, AAA+ lid domain 657 - 702 IPR041569-2

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESNNGIILR VAEANSTDPG MSRVRLDESS RRLLDAEIGD VVEIEKVRKT VGRVYRARPE
70 80 90 100 110 120
DENKGIVRID SVMRNNCGAS IGDKVKVRKV RTEIAKKVTL APIIRKDQRL KFGEGIEEYV
130 140 150 160 170 180
QRALIRRPML EQDNISVPGL TLAGQTGLLF KVVKTLPSKV PVEIGEETKI EIREEPASEV
190 200 210 220 230 240
LEEVSRISYE DIGGLSEQLG KIREMIELPL KHPELFERLG ITPPKGVILY GPPGTGKTLI
250 260 270 280 290 300
ARAVANESGA NFLSINGPEI MSKYYGQSEQ KLREIFSKAE ETAPSIIFID EIDSIAPKRE
310 320 330 340 350 360
EVQGEVERRV VAQLLTLMDG MKERGHVIVI GATNRIDAID PALRRPGRFD REIEIGVPDR
370 380 390 400 410 420
NGRKEILMIH TRNMPLGMSE EEKNKFLEEM ADYTYGFVGA DLAALVRESA MNALRRYLPE
430 440 450 460 470 480
IDLDKPIPTE ILEKMVVTED DFKNALKSIE PSSLREVMVE VPNVHWDDIG GLEDVKREIK
490 500 510 520 530 540
ETVELPLLKP DVFKRLGIRP SKGFLLYGPP GVGKTLLAKA VATESNANFI SIKGPEVLSK
550 560 570 580 590 600
WVGESEKAIR EIFKKAKQVA PAIVFLDEID SIAPRRGTTS DSGVTERIVN QLLTSLDGIE
610 620 630 640 650 660
VMNGVVVIGA TNRPDIMDPA LLRAGRFDKL IYIPPPDKEA RLSILKVHTK NMPLAPDVDL
670 680 690 700 710 720
NDIAQRTEGY VGADLENLCR EAGMNAYREN PDATSVSQKN FLDALKTIRP SVDEEVIKFY
730 740
RTLSETMSKS VSERRKQLQD QGLYL